Page 1 - Ghidul Serviciilor Medicale Synevo, Ediția 2, Volum 2
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GHIDUL SERVICIILOR MEDICALE
AL LABORATOARELOR SYNEVO CUPRINS
VOLUMUL 2
9. MARKERI ENDOCRINI ............................................................................................................... 7
9.1 Hormoni de glicoreglare ................................................................................................ 8
9.1.1 Insulina .................................................................................................................. 8
9.1.2 Proinsulina intactă ............................................................................................... 10
9.1.3 Peptidul C ............................................................................................................ 13
9.2 Hormoni implicaţi în procesul de creştere ................................................................ 15
9.2.1 hGH (hormon uman de creştere) ........................................................................ 15
9.2.2 IGF-I (Somatomedin C) ....................................................................................... 17
9.2.3 IGF-binding protein 3 (IGFBP-3) ......................................................................... 19
9.3 Markeri de fertilitate ..................................................................................................... 22
9.3.1 FSH (hormon foliculo-stimulant) .......................................................................... 22
9.3.2 LH (hormon luteinizant) ....................................................................................... 25
9.3.3 Estradiol .............................................................................................................. 27
9.3.4 Progesteron ......................................................................................................... 29
9.3.5 SHBG (Sex Hormone Binding Globulin).............................................................. 31
9.3.6 Testosteron .......................................................................................................... 33
9.3.7 Testosteron liber .................................................................................................. 35
9.3.8 Dihidrotestosteron .............................................................................................. 37
9.3.9 Prolactina ............................................................................................................ 39
9.3.10 Inhibina B ........................................................................................................... 42
9.3.11 Hormonul anti-mϋllerian (AMH) .......................................................................... 44
9.3.12 Anexă markeri endocrini..................................................................................... 47
9.4 Markeri de sarcină ........................................................................................................ 51
9.4.1 HCG total (HCG+beta) ........................................................................................ 51
9.4.2 Free beta-HCG .................................................................................................... 54
9.4.3 Estriol neconjugat ................................................................................................ 55
9.5 Screening prenatal anomalii fetale .............................................................................. 58
9.5.1 Dublu test (screening prenatal trimestrul I) ......................................................... 58
9.5.2 Anexă - fişă calcul dublu test............................................................................... 65
9.5.3 Triplu test (screening prenatal trimestrul II) ......................................................... 67
9.5.4 Anexă - fişă calcul triplu test................................................................................ 73
9.6 Markeri tiroidieni ............................................................................................................ 75
9.6.1 FT3 (triiodotironina liberă) ................................................................................... 75
9.6.2 FT4 (tiroxina liberă) ............................................................................................. 77
9.6.3 T3 (triiodotironină) ............................................................................................... 78
9.6.4 T4 (tiroxină) ......................................................................................................... 80
9.6.5 TSH (hormonul stimulant al tiroidei – tirotropina) ................................................ 82
9.7 Markeri suprarenalieni .................................................................................................. 85
9.7.1 ACTH................................................................................................................... 85
9.7.2 Cortizol seric........................................................................................................ 87
9.7.3 Cortizol urinar ...................................................................................................... 89
9.7.4 DHEA-S (dehidroepiandrosteron sulfat) .............................................................. 90
9.7.5 Androstendion ..................................................................................................... 92
9.7.6 17-cetosteroizi urinar ........................................................................................... 95
9.7.7 17-hidroxiprogesteron ......................................................................................... 97
9.8 Sistemul renină-angiotensină-aldosteron .................................................................. 99
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