Page 128 - Ghidul Serviciilor Medicale Synevo, Ediția 2, Volum 3

18 TESTE DE BIOLOGIE MOLECULARĂ GHIDUL SERVICIILOR MEDICALE
AL LABORATOARELOR SYNEVO

induse de forţe de frecare crescute (stenoză aortică, defect septal ventricular), trombocitoză marcată,
îndepărtarea FVW din circulaţie datorită legării de celule tumorale (tumoră Wilm`s sau anumite boli
limfoproliferative), scăderea sintezei FVW (hipotiroidism), medicamente (acid valproic, ciprofloxacin,
griseofulvin) .
3
Bibliografie

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2. Friedman K, Rodgers G. „Inherited Coagulation Disorders”. În Wintrobe`s Clinical Hematology,
Greer J, Foerster J, Lukens J, Rodgers G, Pareskevas F, Glader B, 11 ed, Lippincott Williams
th
& Wilkins, 2004, 1392-94.
3. Goodeve A, James P. „von Willebrand Disease”. GeneReviews, NCBI Bookshelf.
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5. Keeney S, Bowen D, Cumming A, Enayat S, Goodeve A, Hill M. „The molecular analysis of
von Willebrand disease: a guideline from the UK Haemophilia Centre Doctors’ Organisation
Haemophilia Genetics Laboratory Network”. In Haemophilia, (2008); 14: 1099–111.
6. Laborator Synevo. Referinţele specifice tehnologiei de lucru utilizate, 2010. Ref Type: Catalog.
7. Mayo Clinic, Mayo Medical Laboratories. Reference Laboratory Services for Health
Care Organizations. von Willebrand Disease 2N (subtype Normandy), Blood. www.
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8. Online Mendelian Inheritance in Man, McKusick-Nathans Institute of Genetic Medicine, Johns
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